Channel 45539-ampa

General data

• ICG id: 2886
• ModelDB id: 45539
• Reference: Traub RD, Contreras D, Whittington MA (2005): Combined experimental/simulation studies of cellular and network mechanisms of epileptogenesis in vitro and in vivo.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: layer 5, layer 2/3, thalamocortical circuit, layer 6, layer 4
• Neuron Region: unspecified
• Neuron Type: pyramidal cell, fast rhythmic bursting (FRB), thalamocortical relay cell (TC, TCR), thalamic reticular (RE) cell, regular spiking (RS) cell, intrinsically bursting (IB) cell, fast-spiking (FS) cell, low-threshold spiking (LTS) cell, interneuron, stellate cell, spiny cell, nontufted cell, tufted cell
• Subtype: AMPA

Metadata generic

• Age: adult
• Authors: M Lazarewicz.
• Comments: Modeling based on traub et al. (1994) and traub et al. (2003c), conductances from traub et al. 2003 and cunningham et al. 2004. This mod file: this is exp2syn.mod modified so that the time constants are very close to each other. Modeling study, with many neurons in the cortex and thalamus. All neurons contain ka, at varying densities, and ka was taken from a previous model. The animal model info here is from electrophysiology experiments also in this paper, both in vivo and in vitro.
• Temperature: Channel model has no temperature dependence. Experiments done at 34-37 deg C, simulations likely done at physiological temperatures.

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