Comments:
Simple synaptic mechanism derived for first-order kinetics of binding of transmitter to postsynaptic receptors. Written by a destexhe & z mainen mar 1993. Parameters estimated from raman & trussel (1992). This is a modeling study, and the animal model is considered to be rat. The authors compare the model to experimental results mostly in rats (e.g. Magee 1998, spruston et al. 1995) and the morphology used is also from rat (2 months old, cannon et al. 1998, n123). Channel kinetics come from various sources.
Temperature:
No apparent temperature dependence. Simulations were done at 34 deg C.