Channel 137259-KahpM95

General data

• ICG id: 981
• ModelDB id: 137259
• Reference: Baker JL, Perez-Rosello T, Migliore M, Barrionuevo G, Ascoli GA (2011): A computer model of unitary responses from associational/commissural and perforant path synapses in hippocampal CA3 pyramidal cells.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: CA3, hippocampus
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: AHP

Metadata generic

• Age: 4-6 weeks, 23+/-5 days
• Authors: M Migliore, M Lazarewicz
• Comments: Borg-graham type generic k-ahp channel, migliore file modified by m lazarewicz 2001. Ancestor model from hemond et al. (2008), model no. 101629, also for ca3 pyramidal neuron. This model is identical to ancestor model. Modeling study that uses experimental results from hemond et al. (2008, 2009) and perez-rosello et al. (2011). Animal model here reflects the data in these experimental studies. This channel was adapted from model in hemond et al. (2008), model no. 101629.
• Runtime: 70.719
• Temperature: Model fitting was done using experimental characterizations at near physiological temperatures (34-35 deg C)

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp