Channel 148094-cagk
General data
- ICG id: 3021
- ModelDB id: 148094
- Reference: Miceli F, Soldovieri MV, Ambrosino P, Barrese V, Migliore M, Cilio MR, Taglialatela M (2013): Genotype-phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of K(v)7.2 potassium channel subunits.
Metadata classes
- Animal Model: human
- Brain Area: hippocampus, CA1
- Neuron Region: soma, dendrites
- Neuron Type: pyramidal cell
- Runtime Q: Q2
- Subtype: not specified
Metadata generic
- Age: various
- Authors: M Migliore
- Comments: Calcium-activated k channel, modified from moczydlowski and latorre (1983). Taken from shah et al. (2008), model no. 112546, with no changes except that cai is not initialized (line 33) and if statement is removed (line 86). This paper features experiments on human kv7.2 channels, put into a model of a ca1 pyramidal cell which originally was based on rat data. We consider the animal model here to be human, due to the experiments, but note that the kinetics of the channels other than kv7.2 are based on other data.
- Runtime: 69.371
- Temperature: Model has temperature dependence.