Channel 143719-kca

General data

• ICG id: 1259
• ModelDB id: 143719
• Reference: Bianchi D, Marasco A, Limongiello A, Marchetti C, Marie H, Tirozzi B, Migliore M (2012): On the mechanisms underlying the depolarization block in the spiking dynamics of CA1 pyramidal neurons.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: hippocampus, CA1
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: not specified

Metadata generic

• Age: P19-24
• Authors: A Destexhe, Y Poirazi
• Comments: Slow ca-dependent potassium current (sahp), responsible for slow ahp, from destexhe et al. (1994), modified by y poirazi 2001. From poirazi et al. (2003), model no. 20212, with no apparent modification to kinetics. Experimental and modeling results in this paper. The animal model info here is from the experimental results, morphology was reduced to a single compartment.
• Runtime: 72.008
• Temperature: Model has temperature dependence, with default temperature of 36 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp