Channel 135898-h

General data

• ICG id: 848
• ModelDB id: 135898
• Reference: Shu Y, Yu Y, Yang J, McCormick DA (2007): Selective control of cortical axonal spikes by a slowly inactivating K+ current.

Metadata classes

• Animal Model: rat, ferret
• Brain Area: layer 5, prefrontal cortex, cortex
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: h

Metadata generic

• Age: ferret: 7-12 weeks old, rat: P17-22
• Authors: Unknown
• Comments: I-h channel from magee 1998. Not mentioned in the paper. Model is identical to the one used in van welie et al. (2006), model no. 82364, so this is cited as the ancestor. An experimental study on ferret and rat l5 pyramidal neurons, with a simple model of soma and axon at the end specifically for testing the kd channel. The animal model info here is from the experimental procedures.
• Runtime: 14.65
• Temperature: Model has temperature dependence, with q10 set to 4.5 and original kinetics at 33 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp