Channel 124043-h

General data

• ICG id: 559
• ModelDB id: 124043
• Reference: Larkum ME, Nevian T, Sandler M, Polsky A, Schiller J (2009): Synaptic integration in tuft dendrites of layer 5 pyramidal neurons: a new unifying principle.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: layer 5, cortex
• Neuron Region: dendrites, dendritic tuft (apical tuft), basal dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: h

Metadata generic

• Age: 27-53 days old
• Authors: M Migliore
• Comments: I-h channel from magee 1998 for distal dendrites. Taken from migliore et al. (2004), model no. 32992, with addition of extra parameter tau (lines 29, 77), and parameters ‘ehd’ and ‘celsius’ initialized. Features experimental data from rat l5 pyramidal neurons, shown in the animal model info here, as well as modeling.
• Runtime: 14.717
• Temperature: Model has temperature dependence, with original kinetics at 33 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp