Channel 155602-hyperde3

General data

• ICG id: 3441
• ModelDB id: 155602
• Reference: Yu J, Proddutur A, Elgammal FS, Ito T, Santhakumar V (2013): Status epilepticus enhances tonic GABA currents and depolarizes GABA reversal potential in dentate fast-spiking basket cells.

Metadata classes

• Animal Model: rat
• Brain Area: hippocampus, dentate gyrus (DG)
• Neuron Region: soma, dendrites
• Neuron Type: basket cell, fast-spiking (FS) cell
• Runtime Q: Q1 (fast)
• Subtype: h

Metadata generic

• Age: P25-27
• Authors: I Aradi
• Comments: Distal dendritic ih channel kinetics for both ht and control animals, from chen et al. (2001), modeling by i aradi. From dyhrfjeld-johnsen et al. (2007), santhakumar et al. (2005), model no. 124513, with no changes. Animal model is from experiments in paper. Channel kinetics are from previous models of dg network.
• Runtime: 13.04
• Temperature: Model has temperature dependence, with q10 set to 3 and original kinetics at 6.3 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp