Channel 114355-M_h

General data

• ICG id: 210
• ModelDB id: 114355
• Reference: Rabinowitch I, Segev I (2008): Two opposing plasticity mechanisms pulling a single synapse.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: hippocampus, CA1
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: h

Metadata generic

• Age: 5-8 week old
• Authors: M Migliore
• Comments: I-h channel from magee 1998 for distal dendrites, default values are for dendrites and low na. No mention in paper, not sure about ancestor. Ancestry is not clear because this channel is not mentioned in the papers. We use migliore & shepherd (2002), model no. 7659, as ancestor. Mod file has identical kinetics to ancestor. Modeling study with parameters based on previous model. The animal model info here is from migliore et al. (1999).
• Runtime: 14.642
• Temperature: Model has standard temperature dependence, q10 set to 4.5

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp