Channel 128559-iCaL

General data

• ICG id: 799
• ModelDB id: 128559
• Reference: Aguiar P, Sousa M, Lima D (2010): NMDA channels together with L-type calcium currents and calcium-activated nonspecific cationic currents are sufficient to generate windup in WDR neurons.

Metadata classes

• Brain Area: dorsal horn of spinal cord
• Neuron Type: wide dynamic range (WDR) neuron
• Runtime Q: Q3
• Subtype: L-type

Metadata generic

• Authors: A Houweling
• Comments: High-threshold calcium current (l), from mccormick & huguenard (1992) for hippocampal pyramidal cells, modified by a houweling. Taken from houweling & sejnowski (1997), model no. 3808, with no changes to kinetics. Modeling study, with no mention of animal model. Channel kinetics originally from mccormick & huguenard (1992), model for hippocampal pyramidal cells.
• Runtime: 8.074
• Temperature: Model has temperature dependence, with q10 assumed to be 3. Original kinetics were formulated at 23.5 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp