Channel 101629-can2

General data

• ICG id: 5
• ModelDB id: 101629
• Reference: Hemond P, Epstein D, Boley A, Migliore M, Ascoli GA, Jaffe DB (2008): Distinct classes of pyramidal cells exhibit mutually exclusive firing patterns in hippocampal area CA3b.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: CA3, hippocampus
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: N-type

Metadata generic

• Age: 4-6 weeks old
• Authors: M Migliore
• Comments: N-type calcium channel. From migliore et al. (1995), with the following modifications: additional parameters (lines 21-27), removal of tables in functions alph, beth, alpm and betm, additional functions alpmt and betmt (lines 97-103), and modification of procedure rate (lines 123-137). Experimental results (animal model info here) as well as modeling.
• Runtime: 9.164
• Temperature: Model has temperature dependence. Experiments done at 34 deg C, no mention of simulation temperature.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp