Channel 123453-Cav2

General data

• ICG id: 477
• ModelDB id: 123453
• Reference: Akemann W, Lundby A, Mutoh H, Knopfel T (2009): Effect of voltage sensitive fluorescent proteins on neuronal excitability.

Metadata classes

• Animal Model: mouse
• Brain Area: cerebellum, Purkinje cell layer
• Neuron Type: Purkinje cell
• Runtime Q: Q4 (slow)
• Subtype: 2.1

Metadata generic

• Age: P18-27
• Authors: W Akemann
• Comments: Cav2.1 (p-type) calcium channel, hh (m) scheme, no inactivation, modified from khaliq et al (2003), from w akemann april 2007. Taken from p-type channel in akemann & knöpfel (2006), model no. 80769, with the following changes: additional parameter e0 (line 46), q10 changed to 2.7 (line 47), various changes associated with addition of igate variable, additional nonspecific current used. Experiments on voltage sensors using transfected cells. Model uses previous model of purkinje cell (akemann & knopfel 2006, khaliq et al. 2003). Animal model is from ancestor model. The l5 pyramidal cell model is not included.
• Runtime: 8.226
• Temperature: Model has temperature dependence, with default at 22 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp