Channel 121060-chan_CaL12

General data

• ICG id: 430
• ModelDB id: 121060
• Reference: Steephen JE, Manchanda R (2009): Differences in biophysical properties of nucleus accumbens medium spiny neurons emerging from inactivation of inward rectifying potassium currents.

Metadata classes

• Animal Model: rat
• Brain Area: basal ganglia, nucleus accumbens (NAcc)
• Neuron Region: soma, dendrites
• Neuron Type: medium spiny projection (MSP) neuron
• Runtime Q: Q2
• Subtype: HVA

Metadata generic

• Authors: J Moyer
• Comments: L-type hva calcium current for msp neuron. (cal1.2). Model used previously in wolf et al. (2005), and moyer et al. (2007), paper also cites mermelstein et al. (1998) for channel parameers. Taken from cal channel in wolf et al. (2005), model no. 112834, with various changes to the mod file. Modeling study based on several previous studies (mermelstein et al. 1999, wolf et al. 2005), which use rat data.
• Runtime: 7.664
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp