Channel 168148-ca

General data

• ICG id: 4080
• ModelDB id: 168148
• Reference: Stadler K, Bierwirth C, Stoenica L, Battefeld A, Reetz O, Mix E, Schuchmann S, Velmans T, Rosenberger K, Brauer AU, Lehnardt S, Nitsch R, Budt M, Wolff T, Kole MH, Strauss U (2014): Elevation in type I interferons inhibits HCN1 and slows cortical neuronal oscillations.

Metadata classes

• Animal Model: rat
• Brain Area: cortex
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Subtype: HVA

Metadata generic

• Age: 3 week old
• Authors: Stadler K, Bierwirth C, Stoenica L, Battefeld A, Reetz O, Mix E, Schuchmann S, Velmans T, Ros
• Comments: COMMENT 26 Ago 2002 Modification of original channel to allow variable time step and to correct an initialization error. Done by Michael Hines(michael.hines@yale.e) and Ruggero Scorcioni(rscorcio@gmu.edu) at EU Advance Course in Computational Neuroscience. Obidos, Portugal ca.mod Uses fixed eca instead of GHK eqn HVA Ca current Based on Reuveni, Friedman, Amitai and Gutnick (1993) J. Neurosci. 13: 4609-4621. Author: Zach Mainen, Salk Institute, 1994, zach@salk.edu ENDCOMMENT
• Temperature: temp = 23 (degC), q10 = 2.3, tadj = q10^((celsius - temp)/10)

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp