Channel 147757-somacar

General data

• ICG id: 3014
• ModelDB id: 147757
• Reference: Romani A, Marchetti C, Bianchi D, Leinekugel X, Poirazi P, Migliore M, Marie H (2013): Computational modeling of the effects of amyloid-beta on release probability at hippocampal synapses.

Metadata classes

• Animal Model: rat, Long Evans
• Brain Area: CA3, hippocampus
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: R-type

Metadata generic

• Age: unknown
• Authors: Y Poirazi.
• Comments: Ca r type channel with medium threshold for activation used in somatic regions. By y poirazi. Has lower threshold for activation/inactivation and slower activation time constant than the model used in dendritic regions. From bianchi et al. (2012), model no. 143719, with no changes (identical mod file). Animal model from experiments in this paper, model originally for ca1 pyramidal neuron.
• Runtime: 7.403
• Temperature: Model has temperature dependence, default at 34 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp