Channel 115356-CAT

General data

• ICG id: 254
• ModelDB id: 115356
• Reference: Royeck M, Horstmann MT, Remy S, Reitze M, Yaari Y, Beck H (2008): Role of axonal NaV1.6 sodium channels in action potential initiation of CA1 pyramidal neurons.

Metadata classes

• Animal Model: mouse
• Brain Area: hippocampus, CA1
• Neuron Region: soma, dendrites, distal dendrites, apical dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: T-type

Metadata generic

• Age: 17-21 days
• Authors: M Horstmann.
• Comments: T-calcium channel. Gate h, taus kloeckner 1999 and chemin 2002; gate m: lee, dand 1999, q10s from coulter 1989. No model db ancestors. Experimental study along with modeling, with morphology from varona et al. (2000) and kinetics from various sources (see comments). The animal model info here is from the experiments in this paper.
• Runtime: 8.605
• Temperature: Model has temperature dependence, with default temperature of 23 deg C and q10 from Coulter et al. (1989).

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp