Channel 46839-grc_ca

General data

• ICG id: 2016
• ModelDB id: 46839
• Reference: D'Angelo E, Nieus T, Maffei A, Armano S, Rossi P, Taglietti V, Fontana A, Naldi G (2001): Theta-frequency bursting and resonance in cerebellar granule cells: experimental evidence and modeling of a slow k+-dependent mechanism.

Metadata classes

• Animal Model: rat
• Brain Area: granule cell layer, cerebellum
• Neuron Region: single compartment
• Neuron Type: granule cell
• Runtime Q: Q4 (slow)
• Subtype: not specified

Metadata generic

• Age: 18-22 days old
• Authors: E D'Angelo.
• Comments: Ca current for cerebellum granule cell model. Derived from high-threshold ca2+ currents (mostly n-type) from rossi et al (1994). Fast second-order activation kinetics and slow voltage-dependent inactivation. This paper contains experimental results from recordings in rat cerebellar slices (18-22 days old). This channel's kinetics are from rossi et al. (1994), also for cerebellar granule cells.
• Runtime: 10.052
• Temperature: Model has temperature dependence. Experiments done at room temperature and simulations done at 30 deg C, with q10=3.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp