Channel 144526-CaT

General data

• ICG id: 1470
• ModelDB id: 144526
• Reference: Hallermann S, de Kock CP, Stuart GJ, Kole MH (2012): State and location dependence of action potential metabolic cost in cortical pyramidal neurons.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: layer 5, cortex
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Runtime Q: Q1 (fast)
• Subtype: T-type

Metadata generic

• Age: 3-5 weeks old
• Authors: Z Mainen, S Hallermann, M Kole
• Comments: Ca.mod to lead to thalamic ca current inspired by destexhe and huguenard, uses fixed eca instead of ghk eqn. According to paper, this is adapted from ca.mod in mainen & sejnowski (1996), model no. 2488. However, it may have been taken from kole et al. (2006), model no. 64195, or a similar model. Electrophysiological recordings with modeling from previously created models. The animal model info is from the experimental data. The neuronal morphology for the model came from experimental reports from in vivo and in vitro l5 pyramidal neurons.
• Runtime: 6.838

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp