Channel 144482-casoma

General data

• ICG id: 1377
• ModelDB id: 144482
• Reference: Delgado JY, Gomez-Gonzalez JF, Desai NS (2010): Pyramidal neuron conductance state gates spike-timing-dependent plasticity.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: layer 2/3, cortex, auditory cortex
• Neuron Region: soma
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: HVA

Metadata generic

• Age: P14-24
• Authors: Z Mainen
• Comments: Hva ca current (soma) based on reuveni et al. (1993), written by z mainen 1994. Model cites traub et al. (2003) and mainen et al. (1995), but this appears to come from mainen & sejnowski (1996), model no. 2488, with various changes in mod file implementation. Kinetics may be changed. Modeling study, with experimental results (animal model info here), model was taken from two previous models of neocortical pyramidal cells (mainen et al. 1995, traub et al. 2003).
• Runtime: 7.691
• Temperature: Model has temperature dependence, with q10 set to 2.3 and original kinetics at 30 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp