Channel 143719-cat

General data

• ICG id: 1254
• ModelDB id: 143719
• Reference: Bianchi D, Marasco A, Limongiello A, Marchetti C, Marie H, Tirozzi B, Migliore M (2012): On the mechanisms underlying the depolarization block in the spiking dynamics of CA1 pyramidal neurons.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: hippocampus, CA1
• Neuron Region: soma, dendrites, apical dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q3
• Subtype: T-type

Metadata generic

• Age: P19-24
• Authors: Unknown
• Comments: T-type calcium channel. This paper’s channels come from poirazi et al. (2003), model no. 20212, and shah et al. (2008), model no. 112546. Both are listed as ancestor channels, with modifications from both. Experimental and modeling results in this paper. The animal model info here is from the experimental results, morphology was reduced to a single compartment.
• Runtime: 7.801
• Temperature: Model has temperature dependence

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp