Channel 140249-it2
General data
- ICG id: 1162
- ModelDB id: 140249
- Reference: Halnes G, Augustinaite S, Heggelund P, Einevoll GT, Migliore M (2011): A multi-compartment model for interneurons in the dorsal lateral geniculate nucleus.
Metadata classes
- Animal Model: mouse
- Brain Area: lateral geniculate nucleus (LGN)
- Neuron Region: soma, dendrites
- Neuron Type: interneuron
- Runtime Q: Q3
- Subtype: low threshold
Metadata generic
- Age: 29-33 days
- Authors: A Destexhe, G Halnes.
- Comments: Low threshold calcium current, responsible for low threshold spikes (lts), written by a destexhe sept 1992, modified by g halnes jun 2011. Ancestor channel from zhu et al. (1999), model no. 116862. Animal model reflects experimental procedures from this paper, which was used to constrain the model. Channel kinetics based originally on traub & miles (1991) model for hippocampal pyramidal neurons, later adapted by zhu et al. (1999) for thalamic interneurons, model no. 116862.
- Runtime: 8.091
- Temperature: Experiments and simulations done at 36 deg C. Kinetics use q10 value of 3 for activation and 1.5 for inactivation.
Current Response Traces
Activation
Inactivation
Deactivation
Action Potential
Ramp
