Channel 127021-Golgi_Na

General data

• ICG id: 744
• ModelDB id: 127021
• Reference: Botta P, de Souza FM, Sangrey T, De Schutter E, Valenzuela CF (2010): Alcohol excites cerebellar Golgi cells by inhibiting the Na+/K+ ATPase.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: granule cell layer, cerebellum
• Neuron Region: soma
• Neuron Type: Golgi cell
• Runtime Q: Q4 (slow)
• Subtype: not specified

Metadata generic

• Age: 23-26 days old
• Authors: E D’Angelo, T Nieus, A Fontana.
• Comments: Na transient channel with gutfreund parametrization for cerebellum golgi cell model, written by e d'angelo, t nieus, and a fontana 2000. Identical to ancestor channel. Experimental study that uses previous ancestor model. The animal model info here is based on the experimental methods in this paper.
• Runtime: 6.19
• Temperature: Experiments done at 32-33 deg C. Model has standard temperature dependence with q10=3.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp