1. Channels
  2. Na
  3. 168148-nax

Channel 168148-nax

General data

Metadata classes

  • Animal Model: rat
  • Brain Area: layer 5
  • Neuron Region: unspecified
  • Subtype: not specified

Metadata generic

  • Age: 3 week old
  • Authors: Stadler K, Bierwirth C, Stoenica L, Battefeld A, Reetz O, Mix E, Schuchmann S, Velmans T, Ros
  • Comments: COMMENT 26 Ago 2002 Modification of original channel to allow variable time step and to correct an initialization error. Done by Michael Hines(michael.hines@yale.e) and Ruggero Scorcioni(rscorcio@gmu.edu) at EU Advance Course in Computational Neuroscience. Obidos, Portugal na.mod Sodium channel, Hodgkin-Huxley style kinetics. Kinetics were fit to data from Huguenard et al. (1988) and Hamill et al. (1991) qi is not well constrained by the data, since there are no points between -80 and -55. So this was fixed at 5 while the thi1,thi2,Rg,Rd were optimized using a simplex least square proc voltage dependencies are shifted approximately from the best fit to give higher threshold Author: Zach Mainen, Salk Institute, 1994, zach@salk.edu May 2006, set thinf = -59 mV, tha = -35 and vshift = 0 to account for AIS Na channel kinetics Kole, ANU, 2006 ENDCOMMENT
  • Temperature: temp = 23 (degC) : original temp, q10 = 2.3 : temperature sensitivity celsius (degC), tadj = q10^((celsius - temp)/10)

Current Response Traces

Activation
Inactivation
Deactivation
Action Potential
Ramp

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