1. Channels
  2. Na
  3. 157157-Nasoma

Channel 157157-Nasoma

General data

Metadata classes

  • Brain Area: hippocampus
  • Neuron Region: unspecified
  • Neuron Type: pyramidal cell, axo-axonic cell (AAC), basket cell, bistratified cell
  • Subtype: not specified

Metadata generic

  • Authors: Saudargiene A, Cobb S, Graham BP
  • Comments: COMMENT Sodium current for the soma References: 1. Martina, M., Vida, I., and Jonas, P. Distal initiation and active propagation of action potentials in interneuron dendrites, Science, 287:295-300, 2000. soma axon-lacking dend axon-bearing dend Na+ gmax 107 ps/um2 117 ps/um2 107 ps/um2 slope 10.9 mV/e 11.2 mV/e 11.2 mV/e V1/2 -37.8 mV -45.6 mV -45.6 mV 2. Marina, M. and Jonas, P. Functional differences in Na+ channel gating between fast-spiking interneurons and principal neurones of rat hippocampus, J. Physiol., 505.3:593-603, 1997. *Note* The interneurons here are basket cells from the dentate gyrus. Na+ Activation V1/2 -25.1 mV slope 11.5 Activation t (-20 mV) 0.16 ms Deactivation t (-40 mV) 0.13 ms Inactivation V1/2 -58.3 mV slope 6.7 onset of inactivation t (-20 mV) 1.34 ms onset of inactivation t (-55 mV) 18.6 ms recovery from inactivation t 2.0 ms (30 ms conditioning pulse) recovery from inactivation t 2.7 ms (300 ms conditioning pulse) ENDCOMMENT
  • Temperature: celsius = 24 (degC), q10 = 3^((celsius - 24)/10)

Current Response Traces

Activation
Inactivation
Deactivation
Action Potential
Ramp

ICGenealogy 0.3.5 © 2015-2016, CNCB, University of Oxford. All material on this page is in copyright. No reproduction of any part of it may take place without the written permission of the CNCB.