Channel 119266-hha2

In other classes K

General data

• ICG id: 399
• ModelDB id: 119266
• Reference: Markaki M, Orphanoudakis S, Poirazi P (2005): Modelling reduced excitability in aged CA1 neurons as a calcium-dependent process

Metadata classes

• Animal Model: rat
• Brain Area: hippocampus, CA1
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: HH

Metadata generic

• Age: adult
• Authors: Y Poirazi, B Mel, C Gold, M Markaki
• Comments: Hh channel that includes both a sodium and delayed rectifier channel and accounts for sodium conductance attenuation. B mel - modified hh conductances after ojvind et al.; t brannon-added attenuation; y poirazi-modified kdr and na threshold and time constants to be more stable. Updated by m markaki 2003. According to paper, this was taken from poirazi et al. (2003), model no. 20212, with various differences between the mod files. This is strictly modeling, with the model taken from a previous paper. Animal model is from ancestry, and is listed as adult because this is a model of an aged pyramidal cell.
• Runtime: 4.915
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp