Channel 180373-Nap_Et2

General data

• ICG id: 3939
• ModelDB id: 180373
• Reference: Shai AS, Anastassiou CA, Larkum ME, Koch C (2015): Physiology of layer 5 pyramidal neurons in mouse primary visual cortex: coincidence detection through bursting.

Metadata classes

• Animal Model: mouse
• Brain Area: layer 5, cortex
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Subtype: persistent

Metadata generic

• Age: P35-62
• Authors: A Shai
• Comments: mtau deduced from text (said to be 6 times faster than for NaTa) so I used the equations from NaT and multiplied by 6. Modeled according to kinetics derived from Magistretti & Alonso 1999. Corrected rates using q10 = 2.3, target temperature 34, orginal 21.
• Temperature: qt = 2.3^((34-21)/10)

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp