Channel 169457-Nap_Et2

General data

• ICG id: 3932
• ModelDB id: 169457
• Reference: Maki-Marttunen T, Halnes G, Devor A, Witoelar A, Bettella F, Djurovic S, Wang Y, Einevoll GT, Andreassen OA, Dale AM (2016): Functional Effects of Schizophrenia-Linked Genetic Variants on Intrinsic Single-Neuron Excitability: A Modeling Study.

Metadata classes

• Animal Model: generic
• Brain Area: layer 5, cortex, layer 6
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Subtype: persistent

Metadata generic

• Authors: T Maki-Marttunen
• Comments: Na channel. Has comment: "mtau deduced from text (said to be 6 times faster than for NaTa), so equations used were from NaT and multiplied by 6." Modeled according to kinetics derived from Magistretti and Alonso (1999)
• Temperature: Model has temperature dependence. From the Comment section: "Corrected rates using q10 = 2.3, target temperature 34, original 21".

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp