Channel 150621-NaPm

General data

Metadata classes

  • Animal Model: rat
  • Brain Area: basal ganglia, striatum (basal ganglia)
  • Neuron Region: single compartment
  • Neuron Type: medium spiny projection (MSP) neuron
  • Runtime Q: Q2
  • Subtype: persistent

Metadata generic

  • Age: adult
  • Authors: K Biddell
  • Comments: A persistent sodium current, used in used in role of a striatal slowly inactivating potassium current in short-term facilitation of corticostriatal inputs. No apparent modeldb ancestors. Parameters and kinetics partially from rat neostriatum data in chao & alzheimer (1995). Animal model is from in vivo rat data as presented in other mahon et al. (2000) paper. This channel's kinetics and parameters are partially from rat neostriatum data in chao & alzheimer (1995).
  • Runtime: 4.808
  • Temperature: Model has temperature dependence, with original kinetics at 22 deg C and q10 set to 2.5. Simulations performed at 37 deg C.

Current Response Traces

Activation
Inactivation
Deactivation
Action Potential
Ramp