Channel 149100-NaTg

General data

• ICG id: 3246
• ModelDB id: 149100
• Reference: Hay E, Schurmann F, Markram H, Segev I (2013): Preserving axosomatic spiking features despite diverse dendritic morphology.

Metadata classes

• Animal Model: rat
• Brain Area: layer 5, cortex
• Neuron Region: soma, axon
• Neuron Type: pyramidal cell, tufted cell
• Runtime Q: Q2
• Subtype: transient

Metadata generic

• Age: P14
• Authors: E Hay
• Comments: Sodium current. From colbert and pan (2002). Corrected rates using q10 = 2.3, target temperature 34, original 21. Taken from hay et al. (2011), model no. 139653, with extra vshift and slope parameters (lines 17-20). At default, there is no difference in kinetics (vshift set to 0, and slope set to 6). Modeling study, with experiments originally described in le be et al. (2007). Animal model is from there.
• Runtime: 4.607
• Temperature: Model has temperature dependence, with q10 set to 2.3, to correct original kinetics at 21 deg C to simulation temperature here of 34 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp