Channel 148094-naxn

General data

Metadata classes

  • Animal Model: human
  • Brain Area: hippocampus, CA1
  • Neuron Region: soma, dendrites
  • Neuron Type: pyramidal cell
  • Runtime Q: Q2
  • Subtype: not specified

Metadata generic

  • Age: various
  • Authors: M Migliore
  • Comments: Na current for axon, no slow inactivation, modified from jeff magee by m migliore 1997. Added sh to account for higher threshold, 2002. Taken from shah et al. (2008), model no. 112546, with no changes (identical mod file). This paper features experiments on human kv7.2 channels, put into a model of a ca1 pyramidal cell which originally was based on rat data. We consider the animal model here to be human, due to the experiments, but note that the kinetics of the channels other than kv7.2 are based on other data.
  • Runtime: 4.776
  • Temperature: Model has temperature dependence, with q10 set to 2.0 and original kinetics at 24 deg C.

Current Response Traces

Action Potential