1. Channels
  2. Na
  3. 45539-naf2

Channel 45539-naf2

General data

Metadata classes

  • Animal Model: rat
  • Brain Area: layer 5, layer 2/3, cortex, auditory cortex, thalamocortical circuit, parietal cortex, layer 6, layer 4, barrel cortex
  • Neuron Region: soma, dendrites, axon
  • Neuron Type: pyramidal cell, fast rhythmic bursting (FRB), thalamocortical relay cell (TC, TCR), thalamic reticular (RE) cell, regular spiking (RS) cell, intrinsically bursting (IB) cell, fast-spiking (FS) cell, low-threshold spiking (LTS) cell, interneuron, stellate cell, spiny cell, nontufted cell, tufted cell
  • Runtime Q: Q1 (fast)
  • Subtype: fast

Metadata generic

  • Age: adult
  • Authors: T Morse, M Lazarewicz.
  • Comments: Modeling based on traub et al. (1994) and traub et al. (2003c), conductances from traub et al. 2003, model no. 20756, and cunningham et al. 2004. Fast na kinetics based on quantitative data in martina and jonas (1997). This file: second sodium transient current for traub rd et al 2005. This current was present in gabaergic interneurons and spiny stellate cells in traub et al 2005 model. Modified by t morse, 2006: fastnashit init to 0 and slight modification of kinetics on lines, 67, 74. Modeling study, with many neurons in the cortex and thalamus. This channel model is for spiny stellate and gabaergic interneurons. The animal model info here is from electrophysiology experiments also in this paper, both in vivo and in vitro.
  • Runtime: 4.387
  • Temperature: Channel model has no temperature dependence. Experiments done at 34-37 deg C, simulations likely done at physiological temperatures.

Current Response Traces

Activation
Inactivation
Deactivation
Action Potential
Ramp

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