1. Channels
  2. Na
  3. 146026-nat

Channel 146026-nat

General data

Metadata classes

  • Animal Model: rat
  • Brain Area: somatosensory cortex, layer 5, cortex
  • Neuron Region: soma, dendrites, axon, apical dendrites, axon hillock, axon initial segment (AIS), dendritic tuft (apical tuft)
  • Neuron Type: pyramidal cell
  • Runtime Q: Q2
  • Subtype: not specified

Metadata generic

  • Age: 17-25 days old
  • Authors: Z Mainen, MH Kole.
  • Comments: Sodium channel, hh style kinetics, fit to data from huguenard et al (1988) and hamill et al (1991). By z mainen, 1994. Changed params by kole in 2006: tha to -26mv, shift 0 and thing -55mv to comply with measured somatic na+ kinetics in neocortex, by kole. A second v-shift was introduced in the initial segment (colbert and pan, 2002). Ancestor channel is from kole et al. (2006), model no. 64195. Modeling study that uses experimental data (somatic voltage responses) from bekkers and hausser (2007), which is reflected in the animal model here. Ancestor channel also from study on somatosensory cortex.
  • Runtime: 4.581
  • Temperature: Experiments referenced in paper (Bekkers and Hausser 2007) done at 32-34 deg C. Original channel temperature was 23 deg C, and q10 is 2.3.

Current Response Traces

Activation
Inactivation
Deactivation
Action Potential
Ramp

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