Channel 146026-nap

General data

• ICG id: 2838
• ModelDB id: 146026
• Reference: Bahl A, Stemmler MB, Herz AV, Roth A (2012): Automated optimization of a reduced layer 5 pyramidal cell model based on experimental data.

Metadata classes

• Animal Model: rat
• Brain Area: somatosensory cortex, layer 5, cortex
• Neuron Region: soma
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: persistent

Metadata generic

• Age: 17-25 days old
• Authors: M Lazarewicz.
• Comments: Sodium persistent current for rd traub, 2003. Implemented by m lazarewicz, 2003. Ancestor channel is not clear, but likely originally from traub et al. 2003, model no. 20756, with a few differences including the addition of vshift parameter. This model is not mentioned in the paper. Modeling study that uses experimental data (somatic voltage responses) from bekkers and hausser (2007), which is reflected in the animal model here.
• Runtime: 4.622
• Temperature: Experiments referenced in paper (Bekkers and Hausser 2007) done at 32-34 deg C. Channel does not appear to have any temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp