Channel 144976-naxn

General data

• ICG id: 2810
• ModelDB id: 144976
• Reference: Culmone V, Migliore M (2012): Progressive effect of beta amyloid peptides accumulation on CA1 pyramidal neurons: a model study suggesting possible treatments.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: hippocampus, CA1
• Neuron Region: axon
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: not specified

Metadata generic

• Age: 50 days old
• Authors: M Migliore
• Comments: Na current for axon, no slow inactivation, by m migliore jul 1997. Added sh to account for higher threshold, by m migliore apr 2002. From migliore et al. (2008), with no modification. Modeling study, identical to ancestor model, the animal model info is from the morphology used here.
• Runtime: 5.131
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp