Channel 144976-na3n

General data

• ICG id: 2809
• ModelDB id: 144976
• Reference: Culmone V, Migliore M (2012): Progressive effect of beta amyloid peptides accumulation on CA1 pyramidal neurons: a model study suggesting possible treatments.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: hippocampus, CA1
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: not specified

Metadata generic

• Age: 50 days old
• Authors: M Migliore
• Comments: Na current modified from jeff magee, by m migliore may 1997, added sh to account for higher threshold, m migliore apr 2002. From migliore et al. (2008), model no. 87535, with no modification. Modeling study, identical to ancestor model, the animal model info is from the morphology used here.
• Runtime: 5.286
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp