Channel 115356-Nap

General data

• ICG id: 262
• ModelDB id: 115356
• Reference: Royeck M, Horstmann MT, Remy S, Reitze M, Yaari Y, Beck H (2008): Role of axonal NaV1.6 sodium channels in action potential initiation of CA1 pyramidal neurons.

Metadata classes

• Animal Model: mouse
• Brain Area: hippocampus, CA1
• Neuron Region: soma, axon, axon initial segment (AIS)
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: persistent

Metadata generic

• Age: 17-21 days
• Authors: M Horstmann.
• Comments: Persistent sodium - fast activating and non-inactivating current. No sources mentiioned. Experimental study along with modeling, with morphology from varona et al. (2000). The animal model info here is from the experiments in this paper.
• Runtime: 4.465
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp