Channel 115356-NaIn

General data

• ICG id: 261
• ModelDB id: 115356
• Reference: Royeck M, Horstmann MT, Remy S, Reitze M, Yaari Y, Beck H (2008): Role of axonal NaV1.6 sodium channels in action potential initiation of CA1 pyramidal neurons.

Metadata classes

• Animal Model: mouse
• Brain Area: hippocampus, CA1
• Neuron Region: soma, axon, axon initial segment (AIS)
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: not specified

Metadata generic

• Age: 17-21 days
• Authors: M Horstmann.
• Comments: Intermediate inactivating na current, inactivation from magistretti and alonso 1999. No model db ancestors. Experimental study along with modeling, with morphology from varona et al. (2000) and kinetics partially from yue et al (2005) and magistretti & alonso (1999). The animal model info here is from the experiments in this paper.
• Runtime: 4.566
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp