Channel 9769-naxn

General data

• ICG id: 2551
• ModelDB id: 9769
• Reference: Poolos NP, Migliore M, Johnston D (2002): Pharmacological upregulation of h-channels reduces the excitability of pyramidal neuron dendrites.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: hippocampus, CA1
• Neuron Region: dendrites, distal dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: not specified

Metadata generic

• Age: 6-10 weeks old
• Authors: M Migliore
• Comments: Na current for axon. No slow inactivation. Implemented by m. Migliore jul 1997. From migliore et al. (1999), model no. 2796, with the only change being the addition of sh parameter for higher threshold. This paper features experimental data as well as modeling. The animal model info below reflects the experimental data here. Both the ancestor and this current model feature rat ca1 pyramidal neuron.
• Runtime: 4.953
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp