Channel 87546-naxn

General data

• ICG id: 2497
• ModelDB id: 87546
• Reference: Minneci F, Janahmadi M, Migliore M, Dragicevic N, Avossa D, Cherubini E (2007): Signaling properties of stratum oriens interneurons in the hippocampus of transgenic mice expressing EGFP in a subset of somatostatin-containing cells.

Metadata classes

• Animal Model: mouse
• Brain Area: CA3, hippocampus, CA1, straum oriens (SO), stratum radiatum (SR)
• Neuron Region: unspecified
• Neuron Type: oriens lacunosum-moleculare (O-LM), interneuron
• Runtime Q: Q3
• Subtype: not specified

Metadata generic

• Age: P8
• Authors: M Migliore
• Comments: Na current for axon, no slow inactivation, implemented by m. Migliore jul 1997, added sh to account for higher threshold in 2002. From migliore et al. (1999), model no. 2796, with no modification (identical mod file). Experimental results from mouse slices (animal model info here), and modeling using kinetics from previous models. Morphology on the interneuron was based on experimental results in saraga et al. (2003).
• Runtime: 4.762
• Temperature: Model has temperature dependence. Experiments done at 33-35 deg C, simulations at 34 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp