Channel 8115-INa_traub_shifted

General data

• ICG id: 2373
• ModelDB id: 8115
• Reference: Destexhe A, Rudolph M, Fellous JM, Sejnowski TJ (2001): Fluctuating synaptic conductances recreate in vivo-like activity in neocortical neurons.

Metadata classes

• Animal Model: cat
• Brain Area: prefrontal cortex, cortex, parietal cortex
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: fast

Metadata generic

• Age: 2-4 weeks
• Authors: A Destexhe
• Comments: Fast sodium channel current for action potentials, from model of ina of hippocampal pyramidal cells, traub & miles 1991, with added shift parameter for inactivation only and instantaneous conductance. Written by a destexhe 1996. Paper cites hodgkin-huxley (1952) as well as destexhe and paré (1999). No modeldb ancestors. Animal model comes from the in vitro experiments in paper. Note that model morphology comes from previous study of cat parietal cortex neurons (layers 2/3, 5, 6) from douglas et al. 1991, and contreras et al. 1997.
• Runtime: 4.523
• Temperature: Model has temperature dependence, default at 36 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp