Channel 114394-nax

General data

Metadata classes

  • Animal Model: Wistar, rat
  • Brain Area: somatosensory cortex, layer 5, cortex
  • Neuron Region: axon, axon initial segment (AIS)
  • Neuron Type: pyramidal cell
  • Runtime Q: Q1 (fast)
  • Subtype: not specified

Metadata generic

  • Age: 2-4 weeks old
  • Authors: Z Mainen
  • Comments: Sodium channel, h-h style kinetics, fit to data from huguenard et al. (1988) and hamill et al. (1991), written by z mainen 1994. Paper cites mainen et al. (1995), model no. 8210, but this appears to come from mainen & sejnowski (1996), model no. 2488, with similar modifications to this model’s na.mod, but with changes in parameters tha and thinf (lines 43, 51). This paper contains experimental results from rats, as well as modeling based on a previous model. The animal model info here is from the experimental results, the morphology of the model is not specified, could also come from the ancestor model.
  • Runtime: 4.41
  • Temperature: Model has temperature dependence, with original kinetics at 23 deg C, and q10 set to 2.3. Simulations done here at 37 deg C.

Current Response Traces

Action Potential