Channel 52034-nap

General data

• ICG id: 2093
• ModelDB id: 52034
• Reference: Bush PC, Prince DA, Miller KD (1999): Increased pyramidal excitability and NMDA conductance can explain posttraumatic epileptogenesis without disinhibition: a model.

Metadata classes

• Brain Area: layer 5, cortex
• Neuron Region: soma
• Neuron Type: pyramidal cell, regular spiking (RS) cell, intrinsically bursting (IB) cell, fast-spiking (FS) cell, interneuron
• Runtime Q: Q1 (fast)
• Subtype: persistent

Metadata generic

• Authors: W Lytton, P Bush, L Borg-Graham
• Comments: Borg-graham channel model of sodium (note potassium and calcium currents are not recorded), appears to be a duplicate of cah. Model from bush & sejnowski (1994, 1996). No model db ancestors. Modeling study, animal model is considered generic. Channel kinetics come from previous modeling studies of cortical pyramidal neurons.
• Runtime: 4.212
• Temperature: Model has temperature dependence, default at 37 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp