Channel 46839-grg_na

General data

• ICG id: 2023
• ModelDB id: 46839
• Reference: D'Angelo E, Nieus T, Maffei A, Armano S, Rossi P, Taglietti V, Fontana A, Naldi G (2001): Theta-frequency bursting and resonance in cerebellar granule cells: experimental evidence and modeling of a slow k+-dependent mechanism.

Metadata classes

• Animal Model: rat
• Brain Area: granule cell layer, cerebellum
• Neuron Region: single compartment
• Neuron Type: granule cell
• Runtime Q: Q4 (slow)
• Subtype: fast

Metadata generic

• Age: 18-22 days old
• Authors: E D'Angelo.
• Comments: Fast na current for cerebellum granule cell model. Model based on gutfreund et al. (1995), with slower inactivation to reproduce spike adaptation during bursts (mainen et al. (1995)). This paper contains experimental results from recordings in rat cerebellar slices (18-22 days old). This channel's kinetics are from gutfreund et al. (1995), for guinea pig cortical neurons.
• Runtime: 6.019
• Temperature: Model has temperature dependence. Experiments done at room temperature and simulations done at 30 deg C, with q10=3.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp