Channel 46839-grc_pna

General data

• ICG id: 2021
• ModelDB id: 46839
• Reference: D'Angelo E, Nieus T, Maffei A, Armano S, Rossi P, Taglietti V, Fontana A, Naldi G (2001): Theta-frequency bursting and resonance in cerebellar granule cells: experimental evidence and modeling of a slow k+-dependent mechanism.

Metadata classes

• Animal Model: rat
• Brain Area: granule cell layer, cerebellum
• Neuron Region: single compartment
• Neuron Type: granule cell
• Runtime Q: Q4 (slow)
• Subtype: persistent

Metadata generic

• Age: 18-22 days old
• Authors: E D'Angelo.
• Comments: Persistent na current for cerebellum granule cell model. Paper cites d'angelo et al. (1998), model based on gutfreund et al. (1995). This paper contains experimental results from recordings in rat cerebellar slices (18-22 days old). This channel's kinetics are from gutfreund et al. (1995), a study on guinea pig cortical neurons.
• Runtime: 5.247
• Temperature: Model has temperature dependence. Experiments done at room temperature and simulations done at 30 deg C, with q10=3.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp