Channel 37856-pyr

In other classes IH K

General data

• ICG id: 1920
• ModelDB id: 37856
• Reference: Kanold PO, Manis PB (2001): A physiologically based model of discharge pattern regulation by transient K+ currents in cochlear nucleus pyramidal cells.

Metadata classes

• Animal Model: rat
• Brain Area: cochlear nucleus (anteroventral AVCN, ventral VCN, dorsal DCN)
• Neuron Region: single compartment
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: HH

Metadata generic

• Age: P11-17
• Authors: PB Manis
• Comments: Dorsal cochlear nucleus (dcn) pyramidal cell model, based on new hh.hoc file in neuron, from kinetic data in kanold and manis (1999). Contains the following currents: sodium (i_na), noninactivating potassium (i_kni), fast and slowly inactivating potassium (i_kif, i_kis), hyperpolarization activated cation current (i_h), and leak current (i_l). See paper for references for kinetics. No modeldb ancestors. Experimental data as well as modeling, the animal model info from experimental methods.
• Runtime: 5.206
• Temperature: Model has temperature dependence, simulations done at 32 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp