Channel 3493-na_moto
General data
- ICG id: 1827
- ModelDB id: 3493
- Reference: Safronov BV, Vogel W (1995): Single voltage-activated Na+ and K+ channels in the somata of rat motoneurones.
Metadata classes
- Animal Model: rat
- Brain Area: spinal cord, lumbar enlargement (L3-6)
- Neuron Region: unspecified
- Neuron Type: motoneuron
- Runtime Q: Q3
- Subtype: not specified
Metadata generic
- Age: 2-8 days old
- Authors: M Migliore
- Comments: Na current for rat motoneuron from safronov and vogel (1995). Implemented by m.migliore dec. 2001. Note that m is used rather than the usual m^3, and recovery from inactivation is not implemented. From paper, inactivation kinetics were a double exponential with fast and slow components. No modeldb ancestors. Experimental study that was later modeled by m migliore. The animal model info here is from the original experiment.
- Runtime: 4.81
- Temperature: Model has temperature dependence, with q10 set to 2.3 and original kinetics at 22 deg C.
Current Response Traces
Activation
![](/static/icg/traces/2_1827_1.png)
Inactivation
![](/static/icg/traces/2_1827_2.png)
Deactivation
![](/static/icg/traces/2_1827_3.png)
Action Potential
![](/static/icg/traces/2_1827_4.png)
Ramp
![](/static/icg/traces/2_1827_5.png)