Channel 20756-naf

General data

• ICG id: 1684
• ModelDB id: 20756
• Reference: Traub RD, Buhl EH, Gloveli T, Whittington MA (2003): Fast rhythmic bursting can be induced in layer 2/3 cortical neurons by enhancing persistent Na+ conductance or by blocking BK channels.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: layer 2/3, cortex
• Neuron Region: soma, dendrites, axon
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: fast

Metadata generic

• Age: adult
• Authors: M Lazarewicz
• Comments: Sodium transient current for rd traub (2003), implemented by m lazarewicz 2003. Kinetic data from martina & jonas (1997), originally at 22-24 deg c, with the kinetics sped up twofold and rate functions shifted 3.5 mv. Same parameters in axon, soma and dendrites. No modeldb ancestors. Model, along with some experimental results. The animal model here is from the experimental results in this paper. Kinetics previously used in rat hippocampus model (martina & jonas 1997).
• Runtime: 4.459
• Temperature: No temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp