Channel 144490-nap

General data

• ICG id: 1431
• ModelDB id: 144490
• Reference: Sterratt DC, Groen MR, Meredith RM, van Ooyen A (2012): Spine calcium transients induced by synaptically-evoked action potentials can predict synapse location and establish synaptic democracy.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: hippocampus, CA1
• Neuron Region: dendrites, apical dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q1 (fast)
• Subtype: persistent

Metadata generic

• Age: P28-42
• Authors: Unknown, M Migliore, Y Poirazi
• Comments: Na persistent channel used in distal oblique dendrites to assist ca spike initiation. Y poirazi - fixed a type found in the original. Taken from poirazi et al. (2003), model no. 20212, with some changes in implementation and parameters but no apparent modification to kinetics. [this file is from the main directory of model] modeling study, identical to ancestor model save the addition of schaffer collateral spines to dendrites. Experimental results from calcium imaging. Animal model reflects the calcium imaging data. The model was also implemented in two new ca1 pn morphologies but their origin is not clear.
• Runtime: 4.034
• Temperature: No apparent temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp