Channel 101629-naxn

General data

• ICG id: 14
• ModelDB id: 101629
• Reference: Hemond P, Epstein D, Boley A, Migliore M, Ascoli GA, Jaffe DB (2008): Distinct classes of pyramidal cells exhibit mutually exclusive firing patterns in hippocampal area CA3b.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: CA3, hippocampus
• Neuron Region: axon
• Neuron Type: pyramidal cell
• Runtime Q: Q3
• Subtype: not specified

Metadata generic

• Age: 4-6 weeks old
• Authors: M Migliore
• Comments: Na current for axon, no slow inactivation, implemented by m migliore jul 1997, added sh to account for higher threshold apr 2002. Paper cites migliore et al. (1999) and migliore (2003) for kinetics. Migliore (2003), model no 19696, is used because it has all channels. The following modifications exist: addition of shift parameter sh, set to 8 (line 14). Experimental results (animal model info here) as well as modeling.
• Runtime: 4.836
• Temperature: Model has temperature dependence. Experiments done at 34 deg C, no mention of simulation temperature.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp