Channel 143719-nap

General data

• ICG id: 1265
• ModelDB id: 143719
• Reference: Bianchi D, Marasco A, Limongiello A, Marchetti C, Marie H, Tirozzi B, Migliore M (2012): On the mechanisms underlying the depolarization block in the spiking dynamics of CA1 pyramidal neurons.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: hippocampus, CA1
• Neuron Region: dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q1 (fast)
• Subtype: persistent

Metadata generic

• Age: P19-24
• Authors: Unknown, Y Poirazi, C Gold
• Comments: Na persistent channel used in distal oblique dendrites to assist ca spike initiation, modified by c gold 2003, updated by y poirazi 2005. From poirazi et al. (2003), model no. 20212, with modification. Experimental and modeling results in this paper. The animal model info here is from the experimental results, morphology was reduced to a single compartment.
• Runtime: 4.265
• Temperature: Model has no temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp